Differential expression of Cosmc, T-synthase and mucins in Tn-positive colorectal cancers
2018
Background
The Tn neoantigen (GalNAcα1-O-Ser/Thr) is an O-glycan expressed in various types of human cancers. Studies in several Tn-expressing cancer cell lines and pancreatic tumors have identified loss of Cosmc expression caused by either mutations or promoter hypermethylation. In this study, we explored the mechanism(s) for Tn expression in human colorectal cancers (CRC).
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
48
References
23
Citations
NaN
KQI