Coexistence of TERT C228T mutation and MALAT1 dysregulation in primary glioblastoma: new prognostic and therapeutic targets

Secil Ak Aksoy,Melis Mutlu,Berrin Tunca,Hasan Kocaeli,Mevlut Ozgur Taskapilioglu,Ahmet Bekar,Cagla Tekin,Omer Gokay Argadal,Muhammet Nafi Civan,Ismail Seckin Kaya,Pinar Eser Ocak,Şahsine Tolunay

Coexistence of TERT C228T mutation and MALAT1 dysregulation in primary glioblastoma: new prognostic and therapeutic targets

2021

Secil Ak Aksoy
Melis Mutlu
Berrin Tunca
Hasan Kocaeli
Mevlut Ozgur Taskapilioglu
Ahmet Bekar
Cagla Tekin
Omer Gokay Argadal
Muhammet Nafi Civan
Ismail Seckin Kaya
Pinar Eser Ocak
Şahsine Tolunay

Objective: This study was designed to conduct molecular classification based on IDH1/2, TERT, ATRX, and DAXX changes in pediatric and adult primary glioblastoma (GB) and to analyze the potential in...

Keywords:

Death-associated protein 6
IDH1
ATRX
MALAT1
Medicine
TERT C228T
Primary Glioblastoma
molecular classification
Cancer research
Mutation (genetic algorithm)

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