ADAM10 and ADAM17 cleave PD-L1 to mediate PD-(L)1 inhibitor resistance
2020
ADAM10 and ADAM17 expression and soluble PD-L1 (sPD-L1) predict poor prognosis in many malignancies, including in patients treated with PD-(L)1 inhibitors. The mechanism of soluble PD-L1 production...
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