The clinical study of oral cancer

We studied clinically 111 cases of tongue cancers from 1960 to 1978 at the Second Department of Oral and Maxillo-facial Surgery of Tokyo Medical and Dental University, and obtained the following conclusions:1) Of 111 tongue cancer, 77 cases were male and 34 were female the average age was 53.3, the portions were mostly the side edge of the tongue, most frequent chief complaint was pain, and 94.6% was pathologically squamous cell carcinomas.2) Cases treated by surgery were 40, treated by irradiation were 60, treated by surgery and irradiation were 10, And 49 cases of the 111 received chemotherapy.3) The 5-year survival rates of high stage cases (Stage III and IV) wer lower than those of low stage ones (Stage I and II).(The 5-year survival rates; Stage I: 94.7%, Stage II: 69.1%, Stage III: 47.9%, Stage III:(Meta-) 60.2%, Stage III:(Meta+) 36.7%, and Total: 60.5%.)4) The surgery group showed the highest 5-year survival rate (76.6%), followed by the irradiation group (53.3%), and the surgery and irradiation group (50.0%).5) The Differences of 5-year survival rates between the group of cases receiving and those not receiving chemotherapy were not clearly detected.6) Cases with metastasis of cervical lymph nodes treated by neck dissection surgery for the first treatment showed a markedly lower 5-year survival rate (30.8%) than those without lymph node metastasis (85.7%). Cases with metastasis of cervical lymph nodes treated by neck dissection surgery for the second treatment showed a lower 5-year survival rate (33.3%) than those without lymph node metastasis (50.0%).7) Considering those facts, we can state the following: The prognosis of Stage 111 patients with metastasis of cervical lymph nodes were most unfavorable, and some Stage If patients might require more radical treatment.