Activation-Induced Cytidine Deaminase Contributes to Pancreatic Tumorigenesis by Inducing Tumor-Related Gene Mutations
2015
Transgenic mice that express the cytosine deaminase AID develop precancerous pancreatic lesions without the apparent involvement of oncogenes, offering a unique mouse model of pancreatic cancer to analyze mutations involved in later stages of pancreatic carcinogenesis.
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