Variations in Plasma Levels of Substance P and Effects of a Specific Substance P Antagonist of the NK1 Receptor on Preovulatory LH and FSH Surges and Progesterone Secretion in the Cycling Cynomolgus Monkey

Bernard Kerdelhué,Robert F. Williams,Véronique Lenoir,V. Fardin,Paul Kolm,Gary D. Hodgen,Georgeanna Seegar Jones,R. Scholler,Howard W. Jones

Variations in Plasma Levels of Substance P and Effects of a Specific Substance P Antagonist of the NK1 Receptor on Preovulatory LH and FSH Surges and Progesterone Secretion in the Cycling Cynomolgus Monkey

2000

Bernard Kerdelhué
Robert F. Williams
Véronique Lenoir
V. Fardin
Paul Kolm
Gary D. Hodgen
Georgeanna Seegar Jones
R. Scholler
Howard W. Jones

These studies investigated the role of substance P (SP) in the regulation of the hypothalamic-pituitary-ovarian axis in cynomolgus monkeys with normal menstrual cycles. Plasma concentrations of SP wer

Keywords:

Follicular phase
Cycling
Substance P
Menstrual cycle
Follicle-stimulating hormone
Endocrinology
Ovulation
Anterior pituitary
Biology
Luteinizing hormone
Internal medicine
progesterone secretion
Diabetes mellitus
Receptor
plasma concentration
plasma levels
substance p antagonist

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