A case of acute myeloid leukemia with promyelocytic features characterized by expression of a novel RARG-CPSF6 fusion

Christopher A. Miller,Christopher Tricarico,Zachary L. Skidmore,Geoffrey L. Uy,Yi-Shan Lee,Anjum Hassan,Michelle O’Laughlin,Heather K. Schmidt,Ling Tian,Eric J. Duncavage,Malachi Griffith,Obi L. Griffith,John S. Welch,Lukas D. Wartman

A case of acute myeloid leukemia with promyelocytic features characterized by expression of a novel RARG-CPSF6 fusion

2018

Christopher A. Miller
Christopher Tricarico
Zachary L. Skidmore
Geoffrey L. Uy
Yi-Shan Lee
Anjum Hassan
Michelle O’Laughlin
Heather K. Schmidt
Ling Tian
Eric J. Duncavage
Malachi Griffith
Obi L. Griffith
John S. Welch
Lukas D. Wartman

Key Points Novel RARG-CPSF6 fusion in an AML case with promyelocytic features and no evidence of PML - RARA or X- RARA fusion. Gene fusions involving RARG can initiate AML with promyelocytic morphological features.

Keywords:

Fusion
Myeloid leukemia
Cancer research
Gene
Biology
Progressive multifocal leukoencephalopathy
Retinoic acid receptor alpha

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