Efficacy of Photodynamic Antimicrobial Chemotherapy (PACT) to Leishmania brasiliensis: an in vitro study

Introduction: Leishmaniasis is a neglected tropical disease considered caused by parasites of the genus Leishmania. Affects about 12 million people in around 80 countries with 2 to 3 million cases per year. Leishmania braziliensis is the main species that causes cutaneous leishmaniasis in Brazil. Despite many achievements in research, the first-line chemotherapy is still based on antimonials, which are toxic and prone to the phenomenon of drug resistance.