KOVUN PULMONER ADENOMATOzisiNiN EKSFOLivATiF SiTOLOJi VE BRONKOALVEOLAR LAVAJ VONTEMLERi iLE TANISI VE SONUC;:LARIN HisTOPATOLOJiK BULGULARLA KAR~ILA~TIRILMASI

This study was undertaken to examine gross, histopathologic and cytologic findings. and to determine the clinIC-pathologic dIagnostic criteria of sheep pulmonary adenomatosis (PAl, For thIs purpose, 2630 sheep rungs were exammed at a local slaughterhouse in Konya, and PA was found in 102 cases (3.88 %). Grossly. in 74 of 102 cases lobular lesions !n one or more lobes, and in 28 cases larger lesions In all lobes were seen. These lesions were firm , shiny grey·whlle in colour and had grey-white nodules 01 different size on CUI surfaces. Histopathologic examination revealed proliferation and papillary projection of alveolar and bronchiolar epithelium and In some cases neoplastic no· dules in bronchiolar lumina. In 6 cases (5,88 %) metastatic tumors were found in mediastinal lymph nodes. In 53 of 102 sheep 2·25 ml of nasal discharge or sputum was obtained. In 26 cases the cytologic examinations 01 sputum re-vealed groups or clusters and sometimes. single neoplastic cells resembling neoplastic cells in histopathological sec· tlons. Cytologic examinations of touch preparations and smears of bronchoalveolar lavage (BAll lIuld made Irom 102 cases showed groups 01 neoplasllc cells in all cases. Some neoplastic cells in sputum, SAL and louch preparations showed anIsocytosis, anlsonucleosls and occaSional mitotic ligures. In conclusion. PA is a low grade bronchlolo· alveolar carcinoma. It was suggested that SAL may be useful in the diagnosis of PA but cytologIC examinations of sputum have I!mited value.