IMPORTÂNCIA DA HEMOGLOBINA FETAL PARA O TRATAMENTO DA ANEMIA FALCIFORME

Sickle cell anemia is one of the most studied diseases in the world, being quite common in the state of Bahia. Such a disease is caused due to a genetic mutation that affects the beta gene of the red blood cell, generating a structural alteration that leaves it with a shape similar to a sickle. For the treatment of this disease, in recent years it has been considered an unusual alternative, through the induction of increased expression of fetal hemoglobin, the main oxygen carrier of the human neonate. This article explains how this innovative application takes place, while explaining about sickle cell anemia, highlighting its pathophysiology and consequences for the patient.