Cross species application of quantitative neuropathology assays developed for clinical Alzheimer’s disease samples

Silvan R. Urfer,Caitlin S. Latimer,Warren Ladiges,C. Dirk Keene,Sarah J Benbow,Benjamin R. Harrison,Daniel Promislow,Matt Kaeberlein,Brian C. Kraemer,Adrienne Wang,Franco Guscetti,Martin Darvas

Cross species application of quantitative neuropathology assays developed for clinical Alzheimer’s disease samples

2019

Silvan R. Urfer
Caitlin S. Latimer
Warren Ladiges
C. Dirk Keene
Sarah J Benbow
Benjamin R. Harrison
Daniel Promislow
Matt Kaeberlein
Brian C. Kraemer
Adrienne Wang
Franco Guscetti
Martin Darvas

ABSTRACTA major obstacle for preclinical testing of Alzheimer’s disease (AD) therapies is the availability of translationally relevant AD models. Critical for the validation of such models is the a...

Keywords:

Disease
Neuroscience
Neuropathology
Medicine
phospho tau
preclinical testing

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