A Supraglottic Mass in a Pediatric Patient: An Unusual Presentation of Lymphoma

Objective:To present a case of laryngeal lymphoma in a pediatric patient and perform a literature review of this rare entity.Patient:A 13-year-old male presented with a rapidly enlarging right neck mass. Work-up of the neck mass included a computed tomography scan of the neck with contrast and revealed a 2.5 cm right level II neck mass and an asymmetric lobulated soft tissue mass in the right pyriform sinus.Intervention:The patient underwent excisional biopsy of the right supraglottic mass. Once his diagnosis was confirmed, he was treated with a standard lymphoma protocol.Results:Intraoperative frozen analysis revealed a small blue cell tumor. Final pathology demonstrated diffuse large B-cell lymphoma of the germinal center B-cell subtype (GC-DLBCL). The patient underwent treatment with primary chemotherapy 12 days after his original procedure with cyclophosphamide, doxorubicin, vincristine, and prednisone.Conclusion:Laryngeal lymphoma remains extremely rare in the pediatric population. With appropriate t...