DPYD gene polymorphisms in patients with gastrointestinal tumors receiving chemotherapy with 5-fluorouracil.

Oleg I. Kit,Liubov Yu Vladimirova,Natalya N. Timoshkina,Anna E Storozhakova,Natalia A. Petrusenko,Dmitry Yu. Gvaldin,Sergey N. Kabanov,Ludmila A. Ryadinskaya,Natalia M. Tikhanovskaya,Irina L. Popova,Natalia A. Abramova,Natalia Yu. Samaneva,Maria A. Teplyakova,Aza A. Lyanova,Kristina A. Novoselova,E. A. Kalabanova,Yana V Svetitskaya,Vladimir Trifanov,Evgeniy N. Kolesnikov

DPYD gene polymorphisms in patients with gastrointestinal tumors receiving chemotherapy with 5-fluorouracil.

2020

Oleg I. Kit
Liubov Yu Vladimirova
Natalya N. Timoshkina
Anna E Storozhakova
Natalia A. Petrusenko
Dmitry Yu. Gvaldin
Sergey N. Kabanov
Ludmila A. Ryadinskaya
Natalia M. Tikhanovskaya
Irina L. Popova
Natalia A. Abramova
Natalia Yu. Samaneva
Maria A. Teplyakova
Aza A. Lyanova
Kristina A. Novoselova
E. A. Kalabanova
Yana V Svetitskaya
Vladimir Trifanov
Evgeniy N. Kolesnikov

90Background: Complete or partial deficiency of the DPD enzyme due to genetic polymorphisms of the DPYD gene causes acute toxicity of fluoropyrimidines, which are widely used in combination chemoth...

Keywords:

Fluorouracil
Acute toxicity
Internal medicine
Medicine
DPYD
Gastrointestinal tumors
Oncology
Chemotherapy
Gene
Pathology
in patient

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