A Clinico-Pathological Study of 200 Cases of Oral Cavity Lesions.

Lesions involving oral cavity are very common in India especially in areas where tobacco, paan and related products are extensively used. Tongue, lips, floor of mouth, hard & soft palate, gingiva and buccal mucosa are usually involved. The aim and objective of study is to determine the frequency of these lesions and categorize them based on biopsies of such lesions. Oral cancer is 8 th most common in men and ranks 14 th among women worldwide. Two- third of the burden is borne by developing countries and 30% by India alone. 200 Biopsies of oral lesions were included in the study. Paraffin sections and routine H & E staining were done. Out of the total number of 200 patients with oral cavity lesions, neoplastic lesions (51%) were more common than non-neoplastic (38%) and pre-neoplastic lesions (11%). Neoplastic lesions were more common in males (86.3%), uneducated people (66%) and older age group. Among malignant lesions, Squamous Cell Carcinoma was the single most common entity constituting 95.1%. Two cases of verrucous carcinoma and one case each of small cell carcinoma, adenoid cystic carcinoma and acinic cell carcinoma were reported. Tongue was the most common site for malignant lesions (67.6% cases). Categorizing the oral cavity lesions according to histopathological features into various types helped us to know the clinical presentation, treatment and prognosis of the disease. Low socio economic status, smoking and un-education are the major risk factors.