PRMT5 Prevents Dilated Cardiomyopathy via Suppression of Protein O-GlcNAcylation.

Rationale: Protein O-GlcNAcylation is dynamically regulated by two key enzymes, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). Excessive protein O-GlcNAcylation contributes to dilated cardiomyop...