Idiopathic pancreatitis associated with common variable immunodeficiency

Objective: Description of the clinical presentation of idiopathic chronic pancreatitis associated with common variable immunodeficiency. Patient: A 13-year-old boy with a 3-year history of chronic pancreatitis complicated by a large pseudocyst and affected by common variable immunodeficiency. Interventions: Laparotomy and an anastomosis between the pseudocyst and the jejunum were performed. Main outcome measures: Resolution of computed tomographic and endoscopic retrograde cholangiopancreatographic images. Three duodenal biopsies. HLA typing and test for antinuclear antibodies. Results: Absence of identifiable and well known causes of pancreatitis. Conclusions: Chronic pancreatitis may be associated with common variable immunodeficiency in young patients and although the relationship between both diseases remains unclear, an autoimmune process may be involved