Markers of kidney function among SARS-CoV-2 infected patients. A rapid review of the literature

Objective.To summarize the scientific literature on kidney abnormalities associated with SARS-CoV-2 infection. Materials and methods. It was conducted a rapid review using the Cochrane methodology. Results. Pre-existing chronic kidney disease (CKD) in SARS-CoV-2 infected patients ranged from 1-38% and acute kidney injury (AKI) ranged from 2.986.4%.The prognosis of patients with SARS-CoV-2 infection was worse among those with CKD and those with normal remnant kidney function (RKF) that developed AKI. The risk of death was higher (pooled risk ratio =1.49;95%CI: 1.09-2.04) among SARS-CoV-2 infected patients with pre-existing CKD. The RKF markers showed alterations among severe and non-surviving SARS-CoV-2 patients;the most common marker was serum creatinine. Conclusions. The scientific evidence shows the relevance of the evaluation and permanent monitoring of the RKF in SARS-CoV-2 hospitalized patients to improve the prognosis of those with pre-existing CKD as well as the prognosis of those without CKD who develop AKI.