Kidney: Hereditary Disorders

Hereditary disorders of the kidney consist of a heterogeneous group of diseases characterized by abnormalities in the ability of the kidneys to filter waste products and/or maintain acid–base and fluid homeostasis. Elucidation of the underlying genetic lesions has enhanced our basic understanding of renal physiology, as well as of normal kidney development and cellular differentiation. Keywords: kidney diseases; kidney development; ion transport; hypertension; acid–base balance; electrolytes