Recent advance in K+-Cl- co-transporter 2 in nervous system disease

K+-Cl- cotransporter2 (KCC2) is abundantly expressed in most mature mammalian central neurons. Numerous studies have indicated that KCC2 is closely related to the pathogenesis of many kinds of nervous system diseases. In this review, we focus on the current research progress of the role of KCC2 in nervous system disease. Key words: K+-Cl- cotransporter 2; Nervous system disease; Research progress