Manifestaciones reumatológicas y sistémicas en pacientes con enfermedad inflamatoria intestinal

Introduction: Inflammatory Bowel Disease (IBD) includes Crohn's Disease (CD) and Ulcerative Colitis (UC). The frequency of systemic involvement in IBD is between 20 and 40%, and most common mani- festations are dermatologic, ocular, articular and hepatobiliary. In the absence of data on the frequency and characteristics of such events in our population, we decided to evaluate the prevalence of extrain- testinal manifestations in argentinian patients diagnosed with IBD, evaluate their characteristics, determine its association with UC and/ or CD and examine the radiographic engagement of these patients. Materials and Methods: 95 consecutive patients with an estab- lished diagnosis of IBD were included. A questionnaire was com- pleted collecting demographic and clinical data of IBD patients. Two physicians performed a complete rheumatological examination. Ra- diographs were read by an independent investigator blinded to the clinical data of patients. Results: 95 patients were included, 39.9% were male. The median age was 37 years and median duration of IBD was 6 years. 75.8% had UC and 22.11% CD, one patient had both diagnoses (UC and CD) and one had undifferentiated intestinal disease. The most frequent non-rheumatological manifestations were 38.9% oral ulcers, uveitis 10.5%, cervicitis/urethritis 8.4%, erythema nodosum 6.3%, psoria- sis 2.1% and pyoderma gangrenosum 1.1%. As for rheumatological manifestations: inflammatory back pain 44.2%, peripheral arthritis 27.4%, heel pain 24.2%, dactylitis 13.7% and enthesitis 11.6%. No significant differences in the frequency of these manifestations be- tween different types of IBD were observed. Sacroiliitis with greater than or equal to 2 graduation was detected in 23.8% of patients, and this was significantly more frequent in patients with CD. Radiological sacroiliitis was present in 16 patients remain asymptomatic in 62.5% and in all cases was asymmetric. Discussion: The analysis of our data confirms the characteristics re- ported in other series. We believe it is important to have data of our patients with inflammatory bowel disease.