Glycemic Variability and Hemoglobin A1c and Their Associations with Blood Pressure Among Overweight Adults with Prediabetes or Type 2 Diabetes (P12-008-19)

Objectives Hemoglobin A1c (HbA1c) is associated with hypertension in prediabetes (PD) and type 2 diabetes (T2D), both of which are associated with increased cardiovascular disease (CVD) risk. Traditionally, HbA1c is the standard approach to assessing glycemic status, however, glycemic variability (GV)—the daily fluctuations in blood glucose concentrations—may be more predictive of CVD. Little is known regarding the relationship between GV and blood pressure (BP). Therefore, we examined GV and HbA1c and their associations with BP in overweight adults with PD and early stage T2D enrolled in a weight loss study.