Vasculitis inducida por cocaína

Normal 0 21 false false false MicrosoftInternetExplorer4 El espectro de lesiones cutaneas causadas por la cocaina es amplio. En los ultimos anos, se ha visto un numero creciente de casos de vasculitis anticuerpo anticitoplasma de neutrofilos (ANCA) positivo en pacientes cocainomanos. Uno de los principales responsables seria el levamisol, un antihelmintico conocido por su efecto inmunomodulador, utilizado para adulterar la cocaina. Se presenta el caso de una paciente de 22 anos, adicta a la cocaina, que consulto por presentar lesiones compatibles con vasculitis cutanea. Se analizan la clinica, el laboratorio, la histopatologia y el tratamiento de esta patologia. Palabras clave: vasculitis, cocaina, levamisol. Dermatol. Argent. 2017, 23 (4): 196-198 Cutaneous vasculitis following cocaine abuse Abstract The range of skin damage caused by cocaine is wide. In recent years, a growing number of cases of antineutrophil cytoplasmic antibody (ANCA) vasculitis have been seen in cocaine addict patients. The cause would be the levamisole, an anthelmintic known by its immunomodulatory effect, used to adulterate cocaine. A case of female patient of 22 years old addicted to cocaine consulted for cutaneous lesions compatible with skin vasculitis is presented. The clinical signs, laboratory, histopathology and treatment of this pathology are discussed. Key words: vasculitis, cocaine, levamisole. Dermatol. Argent. 2017, 23 (4): 196-198 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;}