Association of Hyperhomocysteinemia and Adverse Postoperative Outcomes of on-Pump Primary Isolated Coronary Artery Bypass Grafting Surgery among Postmenopausal Women

Studies investigating the possible role of hyperhomocysteinemia (HHC) in increasing postoperative morbidity and mortality among postmenopausal women undergoing on-pump primary isolated coronary artery bypass grafting (CABG) surgery are sparse in the literature. The knowledge about the relationship of preoperative HHC and postoperative adverse cardiovascular events is not adequately covered. This study is initiated to ascertain the hypothesized higher prevalence of HHC in postmenopausal women with ischemic heart disease (IHD) scheduled for on-pump primary isolated CABG and tracing its association to the proposed adverse postoperative complications especially thromboembolic ones linked in the literature to HHC.