Smad3-mSin3A-HDAC1 Complex is Required for TGF-β1-Induced Transcriptional Inhibition of PPARγ in Mouse Cardiac Fibroblasts

Kaizheng Gong,Mingxing Chen,Rujun Li,Yanghong He,Huajiang Zhu,Dan Yao,Suzanne Oparil,Zhengang Zhang

Smad3-mSin3A-HDAC1 Complex is Required for TGF-β1-Induced Transcriptional Inhibition of PPARγ in Mouse Cardiac Fibroblasts

2016

Kaizheng Gong
Mingxing Chen
Rujun Li
Yanghong He
Huajiang Zhu
Dan Yao
Suzanne Oparil
Zhengang Zhang

Background: We have recently demonstrated that activated transforming growth factor-β (TGF-β) signaling suppresses myocardial peroxisome proliferator-activated re

Keywords:

Cardiac fibrosis
HDAC1
Transforming growth factor
Peroxisome
Endocrinology
Internal medicine
Biology
Diabetes mellitus

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