Clinical observation of tiopronin on treating liver injury caused by antituberculous drugs

Objective:To investigate the efficacy of tiopronin on treating liver injury caused by antituberculous drugs.Methods:The patients were randomly assigned to two groups,61 cases were in the treatment group treated with tiopronin,60 cases in the control group treated with general liver protectant.Results:There was no statistically difference between the treatment group and the control group before treatment(P0.05).After 4 weeks of treatment,there were statistically differences between the treatment group and the control group(P0.05).The normal-ization rate of ALT and TBIL in the treatment group was better than the control group(P0.01).There was 78.69%,91.8% and 100% respectively after 7 d,15 d and 30 d.Conclusion:Tiopronin could be used efficiently in the treatment of liver injury caused by antituberculous drugs.