Oral iron therapy reduced unexplained fatigue in non-anaemic women with serum ferritin concentrations ⩽50 μg/l

Verdon F, Burnand B, Fallab Stubi CL, et al . Iron supplementation for unexplained fatigue in non-anaemic women: double blind randomised placebo controlled trial. BMJ 2003;326:1124–7. [OpenUrl][1][Abstract/FREE Full Text][2] 
 Q Is iron therapy effective for non-anaemic women with unexplained fatigue? Clinical impact ratings GP/FP/Primary care ★★★★★★☆ IM/Ambulatory care ★★★★★★☆ ### ![Graphic][3] Design: randomised, placebo controlled trial. ### ![Graphic][4] Allocation: concealed.* ### ![Graphic][5] Blinding: blinded {patients, clinicians, data collectors, and outcome assessors}†.* ### ![Graphic][6] Follow up period: 1 month. ### ![Graphic][7] Setting: an academic primary care centre and 8 private general practices in western Switzerland. ### ![Graphic][8] Patients: 144 women 18–55 years of age (mean age 35 y, based on n = 136) whose primary reason for consulting was fatigue. Exclusion criteria: anaemia (haemoglobin concentration <117 g/l), other obvious physical or psychiatric causes of fatigue, or chronic fatigue syndrome. ### ![Graphic][9] Interventions: oral, long acting … [1]: {openurl}?query=rft.jtitle%253DBMJ%26rft.stitle%253DBMJ%26rft.issn%253D0007-1447%26rft.aulast%253DVerdon%26rft.auinit1%253DF%26rft.volume%253D326%26rft.issue%253D7399%26rft.spage%253D1124%26rft.atitle%253DIron%2Bsupplementation%2Bfor%2Bunexplained%2Bfatigue%2Bin%2Bnon-anaemic%2Bwomen%253A%2Bdouble%2Bblind%2Brandomised%2Bplacebo%2Bcontrolled%2Btrial%26rft_id%253Dinfo%253Adoi%252F10.1136%252Fbmj.326.7399.1124%26rft_id%253Dinfo%253Apmid%252F12763985%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/ijlink?linkType=ABST&journalCode=bmj&resid=326/7399/1124&atom=%2Febmed%2F9%2F2%2F47.atom [3]: /embed/inline-graphic-1.gif [4]: /embed/inline-graphic-2.gif [5]: /embed/inline-graphic-3.gif [6]: /embed/inline-graphic-4.gif [7]: /embed/inline-graphic-5.gif [8]: /embed/inline-graphic-6.gif [9]: /embed/inline-graphic-7.gif