Abstract 12203: Sotatercept Analog RAP-011 is More Effective Than Sildenafil in Improving Pulmonary Hypertension and Reducing Right Ventricular Hypertrophy in a ZSF1 Rat Model of Heart Failure With Preserved Ejection Fraction

Sachindra R. Joshi,Jun Liu,Patrick Andre,Ravi Kumar,Gang Li

Abstract 12203: Sotatercept Analog RAP-011 is More Effective Than Sildenafil in Improving Pulmonary Hypertension and Reducing Right Ventricular Hypertrophy in a ZSF1 Rat Model of Heart Failure With Preserved Ejection Fraction

2021

Sachindra R. Joshi
Jun Liu
Patrick Andre
Ravi Kumar
Gang Li

Introduction: Pulmonary hypertension (PH) due to heart failure with preserved ejection fraction (PH-HFpEF) is the most prevalent form of WHO Group 2 PH but lacks effective treatment options. We pre...

Keywords:

rat model
Sildenafil
Heart failure with preserved ejection fraction
Cardiology
SOTATERCEPT
Pulmonary hypertension
Right ventricular hypertrophy
Internal medicine
Heart failure
Medicine
Vascular disease

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