Hypoxia and inflammation in the release of VEGF and interleukins from human retinal pigment epithelial cells
2017
Purpose
Retinal diseases are closely associated with both decreased oxygenation and increased inflammation. It is not known if hypoxia-induced vascular endothelial growth factor (VEGF) expression in the retina itself evokes inflammation, or whether inflammation is a prerequisite for the development of neovascularization.
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