Reply to “The Brain, Amphotericin B, and P-Glycoprotein”

We thank David A. Stevens et al. ([1][1]) for [the letter][2] suggesting different results regarding the effect of P-glycoprotein on the brain concentration of amphotericin B (AMB) by P-glycoprotein knockout mice. In contrast to our finding that blockage of P-glycoprotein with inhibitors enhances