Antioxidant and anti-proliferative capacity of extractable phytochemicals from tropical fruits (pineapple, mango and papaya) (1045.18)

Fruits and vegetables (F&V) are universally promoted as healthy and prospective cohort studies support the evidence that their consumption is associated with a lower risk of all-cause mortality and death from cardiovascular disease & cancer. In particular, tropical fruits such as Mango (MA, Mangifera indica cv. Ataulfo), papaya (PM, Carica papaya cv. Maradol) and pineapple (PE, Anana comosus cv. Esmeralda) have a vast array of phytochemicals with antioxidant and anti-carcinogenic potential. The aim of this study was to compare the antioxidant profile and anti-proliferative capacity of hydro-methanolic (20:80 v/v) extracts obtained from freeze-dried pulps of these fruits. MA had 2.3 & 2.7 more phenolic compounds (9.9±0.2 mgGAE/g DM) and 0.6 & 54.6 more ascorbic acid (956±2.2 mg/g DM) than PM or PE, respectively while PE had 0.2 & 2.8 more flavonoids (0.5±0.1 mgQE/g DM) than MA or PM. MA was more effective in scavenging DPPH and ABTS radicals (IC50 5.0 and 5.6 mg/mL) than PM (IC50 18.0 a...