Inhibition of the nuclear factor-κB pathway prevents beta cell failure and diet induced diabetes in Psammomys obesus.

Competing Interests: Morten F. Tonnesen, Flemming Pociot, Thora B. Bodvarsdottir and Allan E. Karlsen are employed by Novo Nordisk A/S. The drug (IKKβ-inhibitor) used in this study is not a Novo Nordisk patent, product in development or marketed product, etc., and it does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. Funding: This work was supported by PhD grants from Novo Nordisk A/S and the Danish Agency for Science, Technology and Innovation under the Danish Ministry of Science, Technology and Innovation. The funders Danish Agency for Science, Technology and Innovation had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Novo Nordisk A/S employed one co-author so had a role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.