Long Term Cocaine Abuser Present with Systemic Sclerosis Like Symptom

Background: Cocaine is one of the most commonly used illicit drugs in the United States. Systemic sclerosis is an autoimmune/connective tissue disease. Diagnosis based on clinical symptoms and positive serum markers. Case presentation: We present a case of an elder African American male with long history of cocaine abuse who presented with dry cough, dyspnea, dysphagia, skin tightness, and color changes. Conclusion s : Systemic sclerosis is typically seen in young females with positive serum markers, but our patient, an older male with long history of cocaine abuse presented with classic systemic sclerosis like symptoms with negative serology. Long term Cocaine use can be present like systemic sclerosis like symptoms. It can be differentiated from autoimmune induced systemic sclerosis with positive serum markers. Treatment would be Symptomatic management with proton pump inhibitors and calcium channel blockers along with substance abuse cessation.