Impact of Splenectomy on Thrombocytopenia, Chemotherapy, and Survival in Patients with Unresectable Pancreatic Cancer

Timothy R. Donahue,Kevork Kazanjian,William H. Isacoff,Howard A. Reber,O. Joe Hines

Impact of Splenectomy on Thrombocytopenia, Chemotherapy, and Survival in Patients with Unresectable Pancreatic Cancer

2010

Timothy R. Donahue
Kevork Kazanjian
William H. Isacoff
Howard A. Reber
O. Joe Hines

Background Patients with unresectable pancreatic cancer (PDAC) or endocrine tumors (PET) often develop splenic vein thrombosis, hypersplenism, and thrombocytopenia which limits the administration of chemotherapy.

Keywords:

Venous thrombosis
Surgery
Splenic vein
Endocrine system
Pancreatic cancer
Retrospective cohort study
General surgery
Survival analysis
Splenectomy
Medicine
Chemotherapy
Oncology
Internal medicine
palliative care

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