Oxaliplatin (with 5FU and leucovorin ) in patients above age 70 ( > ) suffering from metastatic colorectal cancer: An observational study

8042 Background: Data on standard chemotherapy in the real elderly are rare. Patients and Methods: We conducted, during 18 months, an observational study of Oxaliplatin in combination with 5-FU and leucovorin (FUFOL) for treatment of metastatic colorectal cancer, in order to assess safety, response rate and exact regimens used in patients below and above 70 years. Twenty-five centres documented 137 patients (57% male, median age 62 years, colon/rectum/other: 64%/30%/6%, ECOG PS 0/1/2/3: 34%/55%/10%/1%, previous chemotherapy: 69%). Total number of administered cycles was 816 (median 6, range 1–23). Results: \batchmode \documentclass[fleqn,10pt,legalpaper]{article} \usepackage{amssymb} \usepackage{amsfonts} \usepackage{amsmath} \pagestyle{empty} \begin{document} \(\underline{\mathrm{Regimen\ used}}\) \end{document}: 71% received Eloxatin at 85mg/m2 every 2 weeks, 18% at 130mg/m2 every 3 weeks, and 11% received other regimens. FUFOL regimens were 37% FOLFOX4, 27% simplified 46h infusion, 21% weekly bolus (Ro...