Reactogenicity and Safety of DTPa Vaccine and Haemophilus influenzae Type b Conjugate Vaccine (Hib) in a Single Injection vs DTPw and Hib as Separate Injections as a Booster Vaccination in 18-Month-Old Children
2001
Objective: To compare the reactogenicity and safety of the administration of diphtheria-tetanus-acellular pertussis (DTPa) and Haemophilus influenzae type b conjugate (Hib) vaccines in one injection with those of the simultaneous administration of diphtheria-tetanus-whole cell pertussis (DTPw) and Hib vaccines in opposite limbs as booster doses to 18-month-old children previously primed with three doses of DTPw and Hib vaccines as a primary vaccination course. Design and Setting: Nonblind, prospective, randomised, multicentre comparative study set in Spain.
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