Functional changes after photodynamic therapy with verteporfin

Objective To investigate image preferences after photodynamic therapy (PDT). Design Prospective, cross-sectional study. Methods Seventeen patients with neovascular age-related macular degeneration were tested by color vision, contrast sensitivity, and near visual acuity (VA) with positive images and negative images before, 1 week after, and 3 months after PDT. Results Before PDT, 13 patients (76%) preferred positive images; the difference was not significant ( P P P Conclusion Although PDT may not alter the neurosensory retina, it may affect intraretinal function by changing image preference.