Non-operative treatment for malignant pheochromocytoma

Treatments for malignant pheochromocytoma include surgical debulking,131I-MIBG radiotherapy,chemotherapy and transcatheter arterial embolization.MIBG radiotherapy and combined chemotherapy of cyclophosphamide,vincristine,dacarbazine are comparable with respect to response rate and toxicity.Inhibition of HSP90 is an important element of multi--modal concepts for therapy of malignant pheochromocytoma.This review focuses on the recent advances in the non-operative treatment for malignant pheochromocytoma. Key words: Malignant pheochromocytoma; 131I-MIBG; Radiotherapy; Chemotherapy