Nonsteroidal-Induced Benign Strictures of the Caecum: A Case Report And Review Of The Literature

A rare complication seen with chronic use of sustained-release non-steroidal anti-inflammatory drugs (NSAIDs) is formation of bowel strictures and diaphragm-like disease with characteristic histological appearance of submucosal fibrosis. They are thought to result from alterations in enterocyte homeostasis. The strictures generally occur in the terminal ileum and right side of the colon with the symptoms of occult blood loss, change in bowel habits, weight loss, obstruction and rarely perforation. We report the case of a women diagnosed with caecal strictures who was taking slow-release diclofenac tablets for osteoarthritis.