Contributions of high resolution computed tomography on early phase of febrile neutropenia induced by chemotherapy

20546 Background: This study was conducted in order to determine the prevalence of lung findings in the early phase of febrile neutropenia with normal chest radiographs (NCR) and to analyze the associate risk groups. Methods: Ethical approval and informed consent were obtained. 31 High Resolution Computed Tomographies (HRCT) were performed on 27 neutropenic patients with less than 72 hours of fever despite of empiric antibiotic treatment, from May 2006 to May 2007. All patients had NCR. The presence and distribution of focal consolidation (FC), ground-glass opacities (GGO), nodules (N), tree-in-bud pattern (TIBP) and halo sign (HS) were assessed by three radiologists. Statistical analysis of the risk factors was performed using Fisher’s exact and Mann-Whitney tests; a p value of less than 0.05 was considered statistically significant. Results: Five (16.1%) patients had respiratory symptoms, 12 (38.7%) had mucositis, 23 (74.2%) had hematological malignancy (HM). 15 patients (48.3%) had HM in complete remis...