Mise au point sur le lymphome testiculaire primaire Primary testicular lymphoma: review

Primary testicular lym- phoma is a rare form of non- Hodgkin's lymphoma. It occurs more frequently in older patients, and it is a potentially lethal disease. For early stages (I and II), the mana- gement consists of orchidectomy followed by chemotherapy combi- ned with monoclonal antibodies directed against the CD20 antigen andscrotalradiotherapy (sanctuary site) with/or without iliac and/or paraaortic lymph node radiothera- py. For advanced stages (III and IV), chemo-immunotherapyisthe treat- ment of choice while scrotal radio- therapy can be discussed. Both in early oradvanced disease, intrathe- cal chemotherapy is necessary to prevent central nervous system relapse. New molecular approa- ches and/or more aggressive treat- mentsaretobeexploredinthisrare disease. To cite this journal: Onco- logie 13 (2011).