Oral tranexamic acid for an additional 24 hours postoperatively versus a single preoperative intravenous dose for reducing blood loss in total knee arthroplasty: results of a randomized controlled trial (TRAC-24)

Paul Magill,Janet C. Hill,Leeann Bryce,Una Martin,Al Dorman,Rosemary Hogg,Christina Campbell,Evie Gardner,Margaret McFarland,Jennifer L. Bell,Gary Benson,David E. Beverland

Oral tranexamic acid for an additional 24 hours postoperatively versus a single preoperative intravenous dose for reducing blood loss in total knee arthroplasty: results of a randomized controlled trial (TRAC-24)

2021

Paul Magill
Janet C. Hill
Leeann Bryce
Una Martin
Al Dorman
Rosemary Hogg
Christina Campbell
Evie Gardner
Margaret McFarland
Jennifer L. Bell
Gary Benson
David E. Beverland

Aims A typical pattern of blood loss associated with total hip arthroplasty (THA) is 200 ml intraoperatively and 1.3 l in the first 48 postoperative hours. Tranexamic acid (TXA) is most commonly gi...

Keywords:

intravenous dose
blood loss
Medicine
Randomized controlled trial
Anesthesia
Tranexamic acid
total knee arthroplasty
Arthroplasty
Oxford knee score
Chi-square test

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