Randomized Phase III Trial of Prophylactic Cranial Irradiation With or Without Hippocampal Avoidance for Small-Cell Lung Cancer (PREMER): A GICOR-GOECP-SEOR Study.

Nuria Rodríguez de Dios,Felipe Couñago,M. Murcia Mejía,Mikel Rico Osés,P. Calvo Crespo,Pilar Samper,Carmen Vallejo,Javier Ras Luna,Itziar Trueba,A. Sotoca,Cristina Cigarral,Núria Farré,R.M. Manero,Xavier Duran,Juan Domigo Gispert,Gonzalo Sánchez-Benavides,Teresa Rognoni,Margarita Torrente,Jaume Capellades,Mar Jiménez,Teresa Cabada,Miguel Blanco,Ana Isabel Reguera Alonso,Juan Martínez-San Millán,José Escribano,Beatriz Santiago González,J.L. López-Guerra

Randomized Phase III Trial of Prophylactic Cranial Irradiation With or Without Hippocampal Avoidance for Small-Cell Lung Cancer (PREMER): A GICOR-GOECP-SEOR Study.

2021

PURPOSERadiation dose received by the neural stem cells of the hippocampus during whole-brain radiotherapy has been associated with neurocognitive decline. The key concern using hippocampal avoidan...

Keywords:

Oncology
Neural stem cell
non small cell
Internal medicine
Medicine
Neurocognitive
hippocampal avoidance
Prophylactic cranial irradiation
Hippocampal formation
Hippocampus
Radiation therapy

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