Rifamycin Sv Application To Subcutanous Tissue For Prevention OfPost-Cesarean Surgical Site Infection
2011
Aim: The aim of this study was to compare the effect of Rifamycin SV
application to subcutaneous tissue for prevention of post-caesarean
wound infection with a traditional method used for preoperative
antisepsis of skin; povidone-iodine and also to calculate cost of the
treatment. Method: In this randomized prospective study, 1272 women
were divided into two groups. Povidone-iodine was used for preoperative
antisepsis and after closure of the skin in the first group. In the
second group povidone-iodine was used in the same way but also
subcutaneous tissue was irrigated with Rifamycin SV before closure of
subcutaneous tissue. Result: Surgical site infection (SSI) was
developed in 12 of 600 patients in the first group. All of them were
superficial incisional SSI. In 2 cases wound was opened up to fascia.
The overall rate of wound infection with pus was 2%. Total cost of 12
patients with SSI was $5386.In the 2nd group, SSI wasn’t develop
in any of the 596 patients. Total cost of the rifamycin SV used for
washing of subcutaneous tissue was $876.12. Conclusion: Rifamycin SV
application to subcutaneous tissue during cesarian effectively prevents
SSI. It decreases both cost and morbidity caused by wound infection.
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