Colon hemangiolymphangioma—a rare case of subepithelial polyp

An asymptomatic 64-year-old man without a relevant clinical history was referred for endoscopic colorectal cancer screening. In the colonoscopy, a polypoid lesion was identified, which was pediculated and measuring about 25 mm at the proximal transverse colon. The lesion was covered by normalappearing mucosa. We performed a miniprobe endoscopic ultrasonography, 12 MHz, which showed a polypoid morphology lesion, which heterogeneous and cystic, with various anechoic cavities separated by different thickness septa, being a part of them incomplete. The lesion was well delimited with regular boarders and located in the submucosa, with interface preservation with the adjacent layers. The size of the lesion was 27.1 by 20 mm. The patient required a definitive diagnosis. The endoscopic resection was performed with a hot snare. There were no complications. The patient is well with no additional colorectal lesions 2 years after the polyp’s resection. The macroscopic examination of the excised specimen showed a circumscribed round polyp, which is 25 mm in diameter, of soft consistency and covered by normal-appearing mucosa. The histological examination showed a lesion with capillary and lymphatic-type blood vessels in mucosa and submucosa; positivity for CD31 and D2-40 was expressed in the endothelial cells of lymphatic vessels. A definitive diagnosis of colon hemangiolymphangioma was made.