Factors associated with healthy-related quality of life in people living with partial foot or transtibial amputation.

Abstract Objectives To determine which demographic, amputation, and health-related factors were associated with health-related quality of life (HR-QoL) in people living with partial foot (PFA) or transtibial amputation (TTA). Design Cross-sectional survey. Setting Community. Participants Adults with unilateral PFA (n=42) or TTA (n=81). Intervention Not applicable. Main Outcome Measures Medial Outcome Short Form (SF-36) version 2. Results Variation in the SF-36 Physical or Mental Component Summary scores were associated with complex interactions between factors including: time since amputation, fatigue, anxiety, depression, pain interference, and physical function. Level of amputation (i.e, PFA or TTA) did not explain a significant part of the variation in either the SF-36 Physical or Mental Component Summary scores. Conclusion Given the complex interactions between factors associated with the physical and mental health components of HR-QoL, there are opportunities to consider the long-term holistic care required by people living in the community with PFA or TTA.