Intermittently-Scanned Continuous Glucose Monitoring data of Polish patients from Real Life Conditions: more scanning and better glycemic control compared to worldwide data.

Background Randomized trials and observational studies have shown that the use of FreeStyle Libre® intermittently-scanned CGMS is associated with improved glycemic indices and quality of life. Material and methods In this retrospective, Real World Data analysis, we described country-specific glucometrics among isCGMS users from Poland and compared them with international data. The analyzed time period for the Polish and worldwide users ranged from August 2016, September 2014, respectively, to August 2020. Results Data from the Polish population were collected from 10,679 readers and 92,627 sensors with 113 million automatically-recorded glucose readings. The worldwide database included information from 981,876 readers and 11,179,229 sensors with 13.1 billion glucose readings. On average, the users of isCGM from Poland performed substantially more scans/day (21.2±14.2 vs. 13.2±10.7), achieved lower eHbA1c (7.0±1.2% vs. 7.5±1.5%), spent more Time-in-Range (TIR) (64.2±17.3% vs. 58.1±20.3%) and less Time-above-Range (TAR) (29.7±18.0% vs. 36.6±21.3%) (p 70% (36.3% vs. 28.8%), but spent more Time-below-Range (TBR) (4.7% vs 3.6%). Our results confirmed that analyzed glucometrics improve as the scan rate frequency increases. However, at a similar scanning frequency to the comparative group, users from Poland achieved lower eHbA1c, higher TIR, lower TAR, but higher TBR. Conclusions We report more scanning and better glycemic control in isCGM users in Poland than worldwide. The cause of this observation remains unknown. Our data also shows that in real-life practice large number of patients may be willing to perform scanning more frequently than it is usually assumed.