The Study of Application of Mathematical Mode in Cisplatin^s Isotone Peritoneal Chemotherapy

Through the peritoneal chemotherapy performed on 6 dog^s measured celiac fluid、femoral vein and portal vein blood drug concentration. The mathematical logic infered the mathematical function of drug diffusion, absorption and absorptive rate. The results provided clinical basis for cisplatin isotone peritoneal chemotherapy as well as established a method for the research of drug release, absorbed dose and absorptive rate.