Isolated Intraluminal Gallbladder Hemorrhage after Anticoagulation Therapy: Report of a Case

The gallbladder hemorrhage is a rare disease. Some reported cases were associated with cholecystitis, trauma, neoplasm, hemophilia or cystic artery aneurysm. Anticoagulation therapy caused some complications due to bleeding tendency. But gallbladder hemorrhage after anticoagulation therapy was rarely reported. We reported a case with gallbladder hemorrhage after anticoagulation therapy. This was an 80 year-old male patient who had anticoagulant-warfarin, for cerebral infarction. He was found to have a gallbladder tumor during routine abdominal ultrasonography for chronic hepatitis B. He underwent laparoscopic cholecystectomy and intraluminal hemorrhage of gallbladder was discovered. We suggested that the patient had gallbladder hemorrhage due to the complication of anticoagulation therapy. We concluded that gallbladder hemorrhage should be included in the differential diagnosis of patients with a gallbladder tumor.