The Slotnick-Goldfarb's syndrome in infertility- (a case report)

A case of the unilateral streaked ovary syndrome is presented with documentation by cytologic, chromosomal, laparoscopic and hormonal studies. This, the Slotnick-Goldfarb's syndrome, is characterized by oligomenorrhoea progressing into secondary amenorrhoea in a normal phenotypic female with a streaked ovary in one adnexa and an hypoplastic ovary in the other. This case presented with secondary amenorrhoea and primary sterility. She was tall with an increased carrying angle and had hypo plastic breasts and underdeveloped external and internal genitalia. Inves­tigations revealed a normal female karyotype, a mid-zonal matura­tion index, low normal urinary ketosteroids and elevated urinary gonadotrophins. Laparoscopy clinched the diagnosis. The aetiology, prognosis and treatment are briefly discussed. Stress is laid on the fact that whilst investigating a case of sterility and amenorrhoea, this new syndrome must be kept in mind.