Problems with topical use of Mohs paste for local recurrence of breast cancer

Recently, several reports have been made concerning topical use of Mohs paste for local recurrence of breast cancer tumors. Since January 2008, after the introduction of Mohs paste for palliation in patients with local recurrences of breast cancer, we have encountered some problems such as pain, draining off of the paste and ulceration of the lesion. In this study, we have reported the advantages and disadvantage of using Mohs paste, the difference in the procedure depending on the purpose, and the management of problems. When using Mohs paste for the purpose of palliative therapy, these side effects are problems we should not ignore to prevent patient pain.